10. Elaine Benes and David Puddy – Seinfeld – These two bickerers are classic comedy fodder. Favorite moments include: their failed attempt to call it quits on a transatlantic flight; their break-up due to Puddy’s overuse of high-fives; and their hilarious meeting with a priest who insists they’ll both burn in Hell, despite Puddy’s affinity for Christian radio.

9. Pam Beesly and Jim Halpert – The Office – Intra-office hook-ups gone wrong can seriously damage your career, but lucky for these two (and for the show’s fans), Jim and Pam were victorious and proved that love can prevail, even in the face of toxic workplace gossip and a meandering, man-child boss.

8. Brian Griffin and Jillian – Family Guy – He’s a talking dog; she’s his dumb, semi-hot, human girlfriend. Need we say more?

7. Ross Gellar and Rachel Green – Friends – If we learned one thing from the reigning on-again/off-again couple of the ‘90s, it’s that persistence pays off: they end up raising a child and living together as if they were spouses, but they get to date other people!

6. Seth Cohen and Summer Roberts – The O.C. – Every teenage, half-Jewish, comic book nerd’s stock skyrocketed after the coupling of babelicious Summer and the garrulous Seth. What girl wouldn’t want her man to create a superhero version of her?

5. Lily Aldrin and Marshall Eriksen – How I Met Your Mother – This quirky duo strikes the perfect balance between mushy teenagers and an old married couple. From college sweethearts to “Mr. and Mrs.,” Lily and Marshall are BFFs who are still down for some spontaneous nookie (on a highway, a pool table, or a bathroom floor) and pounding back pints like freshmen.

4. Serena van der Woodsen and Dan Humphrey – Gossip Girl – She’s got the coolest preppy-chic wardrobe on the Upper East Side, and he’s got perfect hair and heartthrob eyes – clearly, this is a match made in TV heaven. Plus, these two lovebirds get extra points for getting it on off-set, too.

3. Carrie Bradshaw and Mr. Big – Sex and the City – Sure, Mr. Big is as hot as the latest pair of Manolo mules, but it took some of us a while to consider him gush-worthy, what with his commitment issues and his playboy ways. But charm has a potent effect and he eventually won over viewers and – most importantly – the heart of our girl Carrie.

2. Liz Lemon and Jack Donaghy – 30 Rock – Ok, so they’re not technically a couple, but they nag each other as if they were, and the sexual tension bubbling beneath the surface of their verbal warring is obvious to everyone, except maybe Kenneth, the wide-eyed NBC page.

1 . Bill Compton and Sookie Stackhouse – True Blood – He might be tall and handsome, but the only thing “dark” about Vampire Bill is the inside of his coffin. The pallid bloodsucker and his gal add some heat to the already-scorching town of Bon Temps with their fang-tastic romance. Couple-in-real-life bonus: they don’t have to wait until sundown for a steamy tryst.